Meta-analysis of risk factors for falls in patients with maintenance hemodialysis
Objective To systematically evaluate the risk factors of falls in maintenance hemodialysis(MHD)pa-tients.Methods The studies on the risk factors of falls in MHD patients from China National Knowledge Infrastruc-ture(CNKI),Wanfang,VIP,CBM,PubMed,Web of Science,Cochrane Library,and Embase were searched by computer,and RevMan 5.4 software was used for meta-analysis.The search time limit was from the establishment of the database to July 1,2023.Results A total of 19 studies were included,with a total sample size of 107,641.A-mong the 17 factors,10 influencing factors(P＜0.05)included(1)Risk factors:Age(OR=1.03,95％CI was from 1.00 to 1.05,P=0.002),diabetes(OR=1.97,95％CI was from1.42 to 2.73,P＜0.001),age of dialysis(OR=2.23,95％CI was from 1.68 to 2.98,P＜0.001),related dialysis hypotension(IDH;OR=1.93,95％CI was from 1.88 to 1.97,P＜0.001),frailty(OR=1.64,95％CI was from 1.43 to 1.88,P＜0.001),history of falls(OR=1.71,95％CI was from 1.43 to 2.05,P＜0.001),hyperparathyroidism(OR=1.31,95％CI was from 1.15 to 1.49,P＜0.001),hearing or visual impairment(OR=1.58,95％CI was from 1.24 to 2.01,P=0.002),balance and gait(OR=2.23,95％CI was from 1.54 to 3.25,P＜0.01);(2)Protective factors:serum albumin(Alb;OR=0.89,95％CI was from 0.83 to 0.95,P=0.001).Conclusion Age,diabetes,age of dialysis,IDH,frailty,history of falls,hyperparathyroidism,hearing or visual impairment,and balance and gait were all risk factors for falls in MHD patients,and Alb was a protective factor for falls in MHD patients.
万方数据
维普
