目的 系统评价群组化孕期保健模式(GPC)对妊娠期糖尿病(GDM)孕妇血糖控制与妊娠结局的影响。方法 计算机检索PubMed、Web of Science、Springer Link、中国知网(CNKI)、维普(VIP)与万方数据库等数据库中关于GPC对GDM孕妇血糖控制及妊娠结局影响的随机对照试验(RCT),采用Rev Man 5。4。1软件对数据进行meta分析。检索时间为2013年1月1日-2023年1月1日。结果 共纳入6篇文献。meta分析结果表明:干预组(GPC)孕妇空腹血糖[WMD=-0。41,95%CI(-0。49,-0。33),P<0。000 01]、餐后 2 h 血糖[WMD=-0。58,95%CI(-0。77,-0。38),P<0。001)]及妊娠不良结局{妊娠高血压综合征[OR=0。37,95%CI(0。14,0。96),P=0。04]、剖宫产[OR=0。46,95%CI(0。27,0。78),P=0。04]、巨大儿[OR=0。19,95%CI(0。09,0。41),P<0。001]、产后出血[OR=0。19,95%CI(0。06,0。57),P=0。003]}发生情况均低于对照组(传统孕期保健模式),差异均有统计学意义(P<0。05)。结论 GPC能有效控制GDM孕妇血糖,减少妊娠不良结局的发生。
Meta-analysis of effects of group prenatal care on glycemic control and pregnancy outcomes in pregnant women with gestational diabetes mellitus
Objective To systematically evaluate the influence of group prenatal care(GPC)model on blood glu-cose control and pregnancy outcomes in population with gestational diabetes mellitus(GDM).Methods PubMed,Web of Science,Springer Link,Chinese National Knowledge Infrastructure(CNKI),VIP,and Wanfang Database were searched by computer for randomized controlled trials(RCT)on the effect of GPC on glycemic control and pregnancy outcomes in GDM women,and meta-analysis of data was performed by using RevMan 5.4.1 software.The search period was from January 1,2013 to January 1,2023.Results A total of 6 literatures were included.Meta-analysis results showed that the fasting blood glucose(WMD=-0.41,95%CI was from-0.49 to-0.33,P<0.000 01),2-hour postprandial blood glucose(WMD=-0.58,95%CI was from-0.77 to-0.38,P<0.001)in the intervention group(group prenatal care model),P<0.001)and adverse pregnancy outcomes[pregnancy-in-duced hypertension syndrome(OR=0.37,95%CI was from 0.14 to 0.96,P=0.04),cesarean section(OR=0.46,95%CI was from 0.27 to 0.78,P=0.04),macrosomia(OR=0.19,95%CI was from 0.09 to 0.41,P<0.001),and postpartum hemorrhage(OR=0.19,95%CI was from 0.06 to 0.57,P=0.003)]in the intervention group(GPC)were lower than those in the control group(tradition prenatal care),and the differences were statisti-cally significant(P<0.05).Conclusions The GPC could effectively control blood glucose of GDM pregnant women and reduce the occurrence of adverse pregnancy outcomes.