The aim of this paper was to summarize the caring experience for a case of generalized pustular psori-asis(generalized pustular psoriasis,GPP)combined with a stage 4 pressure injury admitted to our hospital in July 2023.Key points of care included:Analysis of skin and systemic conditions,early recognition of GPP;Selecting ap-propriate dressings to treat pustular psoriatic wounds and appropriate pressure reduction tools;Proper observation and management of medication;Objective assessment and provision of nutritional support.After aggressive treatment and care,the patient's wound and general condition improved and he was discharged successfully.