护士进修杂志2024,Vol.39Issue(12) :1315-1321.DOI:10.16821/j.cnki.hsjx.2024.12.015

微创经椎间孔腰椎椎间融合术后手术部位感染的危险因素及预测模型构建

Risk factors and prediction model of surgical site infection after minimally invasive transforaminal lumbar interbody fusion

高敏 刘小兰 袁枭 吴文聪 雷飞 刘小艳
护士进修杂志2024,Vol.39Issue(12) :1315-1321.DOI:10.16821/j.cnki.hsjx.2024.12.015

微创经椎间孔腰椎椎间融合术后手术部位感染的危险因素及预测模型构建

Risk factors and prediction model of surgical site infection after minimally invasive transforaminal lumbar interbody fusion

高敏 1刘小兰 1袁枭 1吴文聪 1雷飞 1刘小艳1
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作者信息

  • 1. 西南医科大学附属医院脊柱外科,四川泸州 646000
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摘要

目的 探讨影响微创经椎间孔腰椎椎间融合术(minimally invasive transforaminal lumbar interbody fu-sion,MI-TLIF)后患者发生手术部位感染(surgical site infection,SSI)的危险因素,构建并验证SSI的列线图模型.方法 回顾性分析2021年6月-2023年6月在我院接受MI-TLIF的患者620例,按7:3随机分为建模组434例和验证组186例.通过单因素和多因素分析SSI的危险因素,利用logistic回归分析构建风险预测模型,并使用列线图展示模型.内部验证阶段利用ROC曲线和校准曲线评估模型预测SSI风险的区分度和准确度.结果 620例MI-TLIF患者中SSI的发病率为4.68%.回归分析结果显示:年龄≥60岁、白蛋白水平<35 g/L、腰椎旁肌肉脂肪浸润、手术持续时间≥4 h和糖尿病是患者发生SSI的危险因素.最终构建的预测模型的ROC曲线下面积为0.920(95%CI为0.855~0.961).校准曲线显示:2组数据模型的预测曲线与实际曲线及理想曲线的偏差较小,模型拟合良好.结论 本研究构建的风险预测列线图模型预测效果较好,可帮助临床医护人员筛选出高危人群并辅助临床护理决策,降低MI-TLIF后患者发生SSI的风险.

Abstract

Objective To explore the risk factors of surgical site infection(SSI)in patients after minimally inva-sive transforaminal lumbar interbody fusion(MI-TLIF),and to construct and validate a nomogram model of SSI.Method A total of 620 patients who underwent MI-TLIF from June 2021 to June 2023 at our hospital was retrospec-tively analyzed,and were randomly divided into a modeling group(434 cases)and a validation group(186 cases)in a 7:3 ratio.Univariate and multivariate analyses were used to identify risk factors of SSI,and a logistic regression analysis was employed to construct a risk prediction model,which was displayed using a nomogram.In the internal validation phase,the ROC curve and calibration curve were used to evaluate the discrimination and accuracy of the model in predicting SSI risk.Results The incidence of SSI in 620 M-TLIF patients was 4.68%.Regression analysis results showed that age≥60 years,albumin level<35 g/L,lumbar paraspinal muscle fatty infiltration,operation duration ≥4h,and diabetes were risk factors for the occurrence of SSI in patients.The final prediction model had an area under the ROC curve of 0.920(95%CI was 0.855-0.961).The calibration curve showed that the deviation between the predicted curve,the actual curve,and the ideal curve of 2 groups of data models was minimal,indica-ting good model fit.Conclusion The nomogram model constructed in this study has a good predictive effect,which can assist clinical healthcare providers in screening high-risk patients and making clinical nursing decisions,and re-duce the risk of SSI in MI-TLIF patients.

关键词

手术部位感染/微创经椎间孔腰椎椎间融合术/列线图/危险因素/护理评估

Key words

surgical site infection/minimally invasive transforaminal lumbar interbody fusion/nomogram/risk factors/nursing evaluation

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出版年

2024
护士进修杂志
贵州省医药卫生学会办公室

护士进修杂志

CSTPCDCSCD
影响因子:2.59
ISSN:1002-6975
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