Ink painting is a type of painting that uses pure ink for artistic creation,with unique aes-thetic connotations,rich language of action art,and unconventional forms of expression.The three-dimen-sional virtual interaction technology provides support for the innovation of ink painting forms.With the help of three-dimensional production software,virtual interaction production software,plane and post-pro-duction software,the artistic characteristics of three-dimensional virtual interaction ink animation are more prominent.The design practice of three-dimensional virtual interactive ink animation includes two categories:design practice based on content subject and visual elements,and design practice based on character models and storyboard composition.In the production process,the basic model setting and ani-mation production,ink rendering effect,and dynamic interaction effect production in the virtual three-di-mensional environment should be implemented according to the process.