Application value of fecal microbiota transplantation for type 1 diabetes mellitus
Type 1 diabetes mellitus(T1DM)is an autoimmune disease in which pancreatic β cells are destroyed,resulting in an absolute lack of insulin.Intestinal microbiota and its metabolites can promote the progression of T1DM by destroying pancreatic β cells,increasing insulin resistance,increasing intestinal permeability,interfering with immune response.Therefore,fecal microbiota transplantation is expected to become a new method for preventing and treating T1DM in the future.This article mainly explores possible pathways for the application of fecal microbiota transplantation in T1DM,including protection of pancreatic β cells,improving insulin resistance,reducing intestinal permeability,and regulating immune responses.
Type 1 diabetes mellitusfecal microbiota transplantationtreatment
万方数据
维普
