华西医学2024,Vol.39Issue(1) :153-158.DOI:10.7507/1002-0179.202304095

不同方法改善口服清肠药口感及不良反应的研究进展

Research progress of different methods to improve the taste and adverse reactions of intestinal cleansing agents

潘杰 马梦迪 林中华 王瑶 隋牮箐
华西医学2024,Vol.39Issue(1) :153-158.DOI:10.7507/1002-0179.202304095

不同方法改善口服清肠药口感及不良反应的研究进展

Research progress of different methods to improve the taste and adverse reactions of intestinal cleansing agents

潘杰 1马梦迪 1林中华 1王瑶 1隋牮箐1
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作者信息

  • 1. 康复大学青岛医院(青岛市市立医院)消化内二科(山东青岛 266001)
  • 折叠

摘要

结肠镜检查是诊断、治疗结肠疾病及早癌筛查的金标准,良好的肠道准备质量,即肠道清洁度,是结肠黏膜病变及其细节充分可视化的前提条件.临床上使用较多的口服肠道清洁剂,如聚乙二醇、硫酸镁等口感差,服药量大,部分患者不能耐受,影响肠道准备的效果.而口含辅助剂、清肠药加辅助剂、采用新型小容量或极低剂量聚乙二醇-抗坏血酸制剂等方法的出现可以降低患者恶心、呕吐等不良反应发生率,提高患者的耐受性、满意度等.该文对国内外改善清肠药口感、减轻不良反应的方法进行综述,为临床提供参考.

Abstract

Colonoscopy examination is the gold standard for diagnosis and treatment of colon diseases and screening for early cancer.Good quality of bowel preparation,which is also called intestinal cleanliness,is the prerequisite for full visualization of colonic mucosal lesions and their details.In clinic,more intestinal cleansing agents,such as polyethylene glycol and magneium suifate,have bad taste and high dosage,which can not be tolerated by some patients and affect the effect of bowel preparation.The use of oral adjuvant,add adjuvant to intestinal cleansing agents,new low-volume or very low-volume polyethylene glycol-ascorbic acid preparation methods,can reduce the incidence of adverse reactions,such as nausea and vomiting in patients,improve their tolerance,satisfaction and so on.This article reviews the methods of improving the taste and reducing the adverse reactions of intestinal cleansing agents at home and abroad to offer references for clinical practice.

关键词

肠道准备/结肠镜检查/清肠药/口感

Key words

Bowel preparation/colonoscopy examination/intestinal cleansing agents/taste

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基金项目

青岛市卫生健康委员会2022年-2024年青岛市医疗卫生优秀青年医学人才培养项目(V市YQ2023Y07)

出版年

2024
华西医学
四川大学华西医院

华西医学

CSTPCD
影响因子:0.744
ISSN:1002-0179
参考文献量12
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