Research progress on molecular targeted drug therapy for myasthenia gravis
Myasthenia gravis(MG)is a common antibody mediated,cell-mediated,and complement dependent neuromuscular junction immune disease.The treatment mainly includes drug therapy(symptomatic therapy,non-specific immunosuppressive therapy,targeted immunotherapy),immune regulation(intravenous injection of human immunoglobulin and plasma exchange),and thymectomy.With the continuous deepening of research on MG treatment,targeted immune regulation of B cells,complement system,and neonatal Fc receptors has become a current research hotspot in the treatment of MG.Compared with traditional immunosuppressants,MG patients have better tolerance to new biological agents.This article elaborates on the research of MG targeted therapy related drugs and summarizes their efficacy and safety in MG treatment,aiming to find more treatment options.
Myasthenia gravisneonatal Fc receptorcytokinecomplement
NETL
NSTL
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