首页|《血液吸附——第30届急性疾病质量倡议工作组专家共识报告》解读

《血液吸附——第30届急性疾病质量倡议工作组专家共识报告》解读

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该文旨在解读第30届急性疾病质量倡议(Acute Disease Quality Initiative,ADQI)工作组关于血液吸附(hemoadsorption,HA)技术的共识报告,为临床实践和研究提供参考.HA已在多种疾病中展现出治疗优势,ADQI工作组对HA技术研究进展进行了评估,确认其短期生物相容性、安全性和技术可行性,及对特定目标分子去除的实验性证明.初步研究显示内毒素吸附对脓毒症有潜在获益.然而,由于临床证据不足,HA仍被视为实验性干预措施.ADQI共识报告着重于填补现有知识空白,指出未来研究方向,为HA技术的临床应用和进一步研究提供重要指导.
Interpretation of Hemoadsorption:Consensus Report of the 30th Acute Disease Quality Initiative Workgroup
This article aims to interpret the consensus report of the 30th Acute Disease Quality Initiative(ADQI)workgroup on hemoadsorption(HA)technology,providing reference for clinical practice and research.HA has shown therapeutic advantages in various diseases.The ADQI workgroup assessed the research progress of HA technology,confirming its clinically acceptable short-term biocompatibility,safety,and technical feasibility,as well as experimental demonstration of specified target molecule removal.Preliminary studies have shown a potential benefit of endotoxin-based HA in sepsis.However,due to insufficient clinical evidence,HA is still considered an experimental intervention.The ADQI consensus report focuses on filling existing knowledge gaps,pointing out future research directions,and providing important guidance for the clinical application and further research of HA technology.

HemoadsorptionAcute Disease Quality Initiativebiocompatibilityinflammationsepsis

关明镜、张凌、潘红菊

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四川大学华西医院肾脏内科/肾脏病研究所(成都 610041)

临汾市中心医院肾脏内科(山西临汾 041000)

血液吸附 急性疾病质量倡议 生物相容性 炎症 脓毒症

国家重点研发计划

2023YFC2411804

2024

华西医学
四川大学华西医院

华西医学

CSTPCD
影响因子:0.744
ISSN:1002-0179
年,卷(期):2024.39(7)