Research progress of decellularized extracellular matrix hydrogel for peripheral nerve injury
Peripheral nerve injury(PNI)is a common neurological dysfunction.In clinical practice,autologous nerve transplantation is used to solve problems related to PNI,such as limited donor resources,neuroma formation and high donor incidence rate.Therefore,searching for new nerve regeneration materials has become a hot research topic.The decellularized extracellular matrix(dECM)hydrogel provides a scaffold for nerve regeneration by removing the cellular components in biological tissues,preserving the extracellular matrix,and is a potential therapeutic material for nerve regeneration.This article reviews the research progress of dECM hydrogel for PNI and looks forward to the clinical prospects of this research direction.
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