高压氧治疗脑小血管病认知功能障碍的研究进展
Research progress of hyperbaric oxygen therapy for cognitive impairment in cerebral small vessel disease
屈芷萱 1曾宪容1
作者信息
- 1. 电子科技大学医学院 四川省人民医院神经内科(成都 610000)
- 折叠
摘要
脑小血管病是指各种原因影响脑内小血管所导致的一系列临床、影像和病理综合征.认知功能障碍是脑小血管病最常见的并发症之一,目前研究显示认知功能障碍与缺氧等多种因素有关,高压氧治疗可以通过改善缺氧达到一定治疗效果.该文综述了脑小血管病的发病机制、脑小血管病的生物标志物、高压氧治疗认知功能障碍的研究进展,并着重阐述了高压氧治疗轻度认知功能障碍和痴呆的研究进展,为临床治疗提供更多参考.
Abstract
Cerebral small vessel disease refers to a series of clinical,imaging,and pathological syndromes caused by various factors affecting small blood vessels in the brain.Cognitive impairment is one of the most common complications of cerebral small vessel disease.Current researches have found that cognitive impairment is related to various factors such as hypoxia.Hyperbaric oxygen therapy can achieve certain therapeutic effects by improving hypoxia.This article reviews the pathogenesis of cerebral small vessel disease,biomarkers of cerebral small vessel disease,research progress on hyperbaric oxygen therapy for cognitive impairment,and focuses on the research progress of hyperbaric oxygen therapy for mild cognitive impairment and dementia,providing more references for clinical treatment.
关键词
脑小血管病/高压氧治疗/认知功能障碍/缺氧/机制Key words
Cerebral small vessel disease/hyperbaric oxygen therapy/cognitive impairment/hypoxia/mechanism引用本文复制引用
出版年
2024
NETL
NSTL
万方数据