首页|丹参酮ⅡA在心血管疾病中的研究进展

丹参酮ⅡA在心血管疾病中的研究进展

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心血管疾病是全球发病率和死亡率最高的疾病之一.丹参酮ⅡA是丹参的主要活性成分之一,能够显著改善心功能.该文综述了丹参酮ⅡA保护心血管的机制,主要包括减少心肌细胞凋亡、抑制炎症反应、改善动脉粥样硬化、抑制心肌纤维化和抗氧化应激,并对丹参酮ⅡA的相关临床研究进行评估,以期为丹参酮ⅡA在心血管系统的后续研究与临床应用提供参考.
Research progress of tanshinone Ⅱ A in cardiovascular diseases
Cardiovascular disease is one of the diseases with the highest morbidity and mortality in the world.Tanshinone ⅡA is one of the main active components of Salvia miltiorrhiza,which can significantly improve heart function.In this paper,the mechanisms of cardiovascular protection by tanshinone ⅡA are reviewed,including reducing myocardial apoptosis,inhibiting inflammatory reaction,improving atherosclerosis,and inhibiting myocardial fibrosis and antioxidant stress,and the related clinical research of tanshinone ⅡA is evaluated,so as to provide reference for the following research and clinical application of tanshinone ⅡA in cardiovascular system.

Tanshinone ⅡAcardiovascular diseasesclinical trialsresearch progress

龙秀鹏、曾雨婷、陶顺、张哲

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湖南医药学院医学院(湖南怀化 418099)

深圳市人民医院心内科(广东深圳 518020)

丹参酮ⅡA 心血管疾病 临床试验 研究进展

2024

华西医学
四川大学华西医院

华西医学

CSTPCD
影响因子:0.744
ISSN:1002-0179
年,卷(期):2024.39(9)