糖尿病与缺血性卒中:病理生理机制及药物研究现状
Diabetes mellitus and ischemic stroke:current pathophysiological mechanisms and pharmaceutical research status
朱婵 1张强 2陈秋3
作者信息
- 1. 四川大学华西第二医院中医科(成都 610041);出生缺陷与相关妇儿疾病教育部重点实验室(四川大学)(成都 610066)
- 2. 四川省骨科医院足踝科(成都 610041)
- 3. 成都中医药大学附属医院/四川省中医院内分泌科(成都 610072)
- 折叠
摘要
糖尿病患者具有缺血性卒中发病率高,病情更严重,卒中再发生及死亡风险更高的特点.目前的研究显示,伴或不伴有糖尿病的缺血性卒中患者在卒中事件发生时病理生理机制不完全相同,相应的,有益于非糖尿病患者的治疗不一定同样有益于糖尿病卒中患者.该文梳理了糖尿病合并缺血性脑卒中的病理生理机制及药物研究现状,为干预糖尿病合并缺血性卒中人群的相关研究提供参考.
Abstract
Diabetes mellitus patients have the characteristics of higher morbidity of ischemic stroke,severe symptoms,more recurrent stroke and higher mortality.Current studies have shown that stroke patients with or without diabetes mellitus have different pathophysiological mechanisms during stroke progress.Accordingly,treatment that is beneficial to non-diabetes mellitus patients may not be beneficial to diabetes mellitus stroke patients.This article reviews the current research status of pathophysiological mechanism of diabetes mellitus complicated with ischemic stroke,and provides reference for the relevant research of drug intervention in diabetes mellitus patients complicated with stroke.
关键词
糖尿病/缺血性脑卒中/机制/药物Key words
Diabetes mellitus/ischemic stroke/mechanisms/pharmaceutical引用本文复制引用
出版年
2024
NETL
NSTL
维普
万方数据