Progress in Structure Modifications and Biological Activities of Chrysin Derivatives
Chrysin is a flavonoid extracted from Oroxylumindicum (L.)Vent,and it showed extensive biological activities,such as antitumor,hypoglycemic,antibacterial,insecticidal,anti-inflammatory and antioxidant,etc.So those important pharmacological activities caused the attention of researchers.However,some works also indicate that there are several disadvantages for chrysin,including poor soluble,poor bioavailability and glycosylation metabolic.Therefore,in order to improve the solubility of chrysin and enhance metabolic stability,a lot of the structure modification works have been made.Many derivatives of chrysin with various biological activities have been obtained in recent years.This work will review the advance in the progress of structure modification of chrysin and biological activities of chrysin derivatives,mainly including anti-tumor,hypoglycemic,antibacterial and other biological activities for the further study of chrysin.
国家科技期刊平台
NSTL
万方数据
维普
