化学试剂2025,Vol.47Issue(1) :1-8.DOI:10.13822/j.cnki.hxsj.2024.0293

中药多糖药理活性最新研究进展

Latest Advancements Research on Pharmacological Activity of Polysaccharides in Chinese Medicine

吕嘉璐 霍燕菊 张翼
化学试剂2025,Vol.47Issue(1) :1-8.DOI:10.13822/j.cnki.hxsj.2024.0293

中药多糖药理活性最新研究进展

Latest Advancements Research on Pharmacological Activity of Polysaccharides in Chinese Medicine

吕嘉璐 1霍燕菊 2张翼1
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作者信息

  • 1. 黑龙江中医药大学教育部北药基础与应用研究重点实验室,黑龙江哈尔滨 150036
  • 2. 黑龙江中医药大学第一临床医学院,黑龙江哈尔滨 150036
  • 折叠

摘要

近年来,中药多糖因较低的毒副作用,多样的药理活性以及广阔的应用前景,成为天然药物开发及应用研究的热点.对近5年的中药多糖研究进行了追踪,汇总整理了中药多糖发挥的抗肿瘤、免疫调节、糖脂代谢、肠道菌群、抗氧化及其他药理活性,并对影响中药多糖药理活性的因素进行了剖析.分析了当前中药多糖研究中存在的局限性,并对未来中药多糖的应用前景进行展望,旨在提高中药材的利用率,明确中药多糖的药理活性,从而加速中药多糖的成果转化及应用推广.

Abstract

In recent years,polysaccharides in traditional Chinese medicine have become a hot spot in the development and application of natural medicines due to their low toxicity and side effects,diverse pharmacological activities,and broad application prospects.We tracked the research on polysaccharides in traditional Chinese medicine in recent years,summarized the anti-tumor,immunomodulatory,glucose and lipid metabolism,intestinal microbiota,antioxidant,and other pharmacological activities of traditional Chinese medicine polysaccharides,and analyzed the factors affecting the pharmacological activities of traditional Chinese medicine polysaccharides.The limitations of the current research on polysaccharides in traditional Chinese medicine was analyzed and the future application prospects of polysaccharides in traditional Chinese medicine was presented,to achieve three aims:first,to improve the utilization rate of traditional Chinese medicines,second,to clarify the pharmacological activity of traditional Chinese medicine polysaccharides,and third,to accelerate the transformation and application of traditional Chinese medicine polysaccharides.

关键词

中药多糖/药理活性/抗肿瘤/免疫调节/肠道代谢稳态调节/作用机制

Key words

traditional Chinese medicine polysaccharide/pharmacological activity/anti-tumor/immune regulation/regulation of intestinal metabolic homeostasis/mechanism

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出版年

2025
化学试剂
中国分析测试协会,国药集团化学试剂有限公司,北京国化精试咨询有限公司

化学试剂

影响因子:0.295
ISSN:0258-3283
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