Singlet oxygen(1O2)is one of reactive oxygen species(ROS),which is excited by molecular triplet oxygen and has good oxidation activity.Compared with other ROS,1O2 has better selectivity and higher activity,so it has greater research value.Since its discovery,people have gradually realized its important role in organic synthesis.1O2 research has promoted the wave of scientific development in the fields of organic chemistry,biochemistry,medicine,environmental chemistry,and food chemistry.This article reviewed the basic properties of 1O2,reviewed the preparation methods of 1O2 including photosen-sitization and chemical methods,as well as key scientific research on the reaction with organic sub-stances,and further evaluated its application value to organic synthesis.High industrial value alcohols,epoxy compounds and carbonyl compounds provide a variety of synthetic reaction pathways,and are effec-tive active components for loading oxygen on organic matter.We hope this article will inspire researchers in related fields to promote the development of the field of organic synthesis.
singlet oxygenphotosensitizationperoxideoxidationorganic synthesis