The two-dimensional(2D)layered MXene materials have excellent physicochemical proper-ties.The nanodot materials prepared by MXenes(MNDs)not only inherit the physical and chemical properties of the two-dimensional layered MXenes material itself,but also exhibit some new properties due to the size effect of the nanodots.This article reviewed MXenes-based nanodot materials comprehen-sively and summarized the preparation methods of MXenes nanodots including Ti3C2,MoC2,and others.Meanwhile,this article compared various common preparation methods,and analyzed the advantages and disadvantages of different methods,on the basis of which the application prospects of such new nanomate-rials in optoelectronic and biomedical fields are summarized.