Current Status of Research on COVID-19 Patients With Concomitant Hyperglycemia and the Management Strategies of Hyperglycemia
The global pandemic of coronavirus disease 2019(COVID-19)poses a serious threat to human health,leading to a relatively high mortality in patients with severe or critical conditions in particular.Hyperglycemia is one of the high-risk factors for poor prognosis in these patients.Patients with COVID-19 are more likely to develop hyperglycemia,regardless of whether there is a previous history of diabetes mellitus.Glucocorticoid therapy is an important part of the anti-inflammatory regimen for COVID-19.However,the use of glucocorticoid significantly increases the occurrence of hyperglycemic events in COVID-19 patients,ultimately leading to poor prognosis.Timely monitoring of blood glucose and early intervention for hyperglycemia contribute to the improvement in the outcome of COVID-19 patients.In this paper,we comprehensively reviewed the potential mechanisms of COVID-19 and concomitant hyperglycemia.We reviewed the latest findings on the blood glucose management strategies for COVID-19 patients with concomitant hyperglycemia,aiming to optimize the management of hyperglycemia in COVID-19 patients and improve the outcome of the disease.