首页|高原相关高血压研究现状与展望

高原相关高血压研究现状与展望

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高原是一种极端的地理环境,其特有的低压低氧、寒冷等地理因素可能对心血管系统及血压调节产生重要影响.高血压作为威胁人类健康的首要心血管危险因素,受遗传及环境等多种因素影响.越来越多的证据表明相较于平原人群,高原地区高血压患病率更高,而知晓率、治疗率及控制率却显著偏低.尽管在过去的几十年里,高原相关高血压的研究进展取得巨大进步,但关于急性与慢性高原暴露人群的血压反应以及相关诊疗规范仍存在争议.本文主要就高原暴露对血压水平的影响以及高原相关高血压的流行病学、机制及治疗建议作简要综述,以便提升高原地区高血压的防治工作水平.
Current Status and Prospects of Research on Altitude-Related Hypertension
The high-altitude environment,an extreme kind of geographical environment characterized by low atmospheric pressure and oxygen levels,coupled with low temperatures,may significantly impact on the cardiovascular system and blood pressure regulation.Hypertension,a primary cardiovascular risk factor threatening human health,is influenced by a variety of genetic and environmental factors.A growing body of evidence suggests the prevalence of hypertension is higher in populations living in high-altitude regions than that in populations living at low altitudes.However,the awareness,treatment,and management rates are significantly lower in high-altitude regions.Despite the tremendous progress made in research on altitude-related hypertension over recent decades,debates persist regarding the blood pressure response of acute and chronic exposure to high altitudes,as well as the relevant diagnosis and treatment protocols.Herein,we made a brief review of the effects of high-altitude exposure on blood pressure,the epidemiology,mechanisms,and treatment recommendations of altitude-related hypertension in order to improve the prevention and treatment of altitude-related hypertension.

High altitudeHypertensionEpidemiologyMechanismTreatmentReview

姚媛媛、张鑫、赵丽明、陈晓平

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四川大学华西医院心脏内科(成都 610041)

四川大学华西医院西藏成办分院心脏内科(成都 610037)

高原 高血压 流行病学 机制 治疗 综述

2024

四川大学学报(医学版)
四川大学

四川大学学报(医学版)

CSTPCD北大核心
影响因子:0.961
ISSN:1672-173X
年,卷(期):2024.55(6)