华西药学杂志2024,Vol.39Issue(1) :110-115.DOI:10.13375/j.cnki.wcjps.2024.01.023

半夏化学成分和药理作用的研究进展及其质量标志物预测分析

Research progress on chemical constituents and pharmacological effects of Pinelliae Rhizoma and predictive analysis of quality marker

张国玉 熊继东 魏家艳 仲楠 强宇靖 李芸
华西药学杂志2024,Vol.39Issue(1) :110-115.DOI:10.13375/j.cnki.wcjps.2024.01.023

半夏化学成分和药理作用的研究进展及其质量标志物预测分析

Research progress on chemical constituents and pharmacological effects of Pinelliae Rhizoma and predictive analysis of quality marker

张国玉 1熊继东 1魏家艳 1仲楠 1强宇靖 1李芸1
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作者信息

  • 1. 甘肃中医药大学药学院甘肃陇药产业创新研究院西北中藏药省部共建协同创新中心,甘肃兰州 730000
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摘要

利用CNKI、PubMed、万方等数据库,对半夏Pinelliae Rhizoma的化学成分及药理作用进行整理,发现左旋麻黄碱、葫芦巴碱、腺苷、胸苷、尿苷、鸟苷、β-谷甾醇、亚油酸、棕榈酸、琥珀酸、苹果酸、天冬氨酸等成分可作为其主要质量标志物,可为半夏的质量控制研究提供基础.

Abstract

In this paper,CNKI,PubMed,Wanfang and other databases were used to sort out the chemical constituents and pharmacological effects of Pinelliae Rhizoma,and on this basis,the quality markers of Pinelliae Rhizoma were predicted and analyzed.The results showed that levoephedrine,trigonelline,adenosine,thymidine,uridine,guanoside,β-sitosterol,linoleic acid,palmitic acid,succinic acid,malic acid and aspartic acid could be used as the main quality markers of Pinelliae Rhizoma,in order to provide the basis for quality control research.

关键词

半夏/化学成分/药理作用/质量标志物/左旋麻黄碱/葫芦巴碱/苷类/β-谷甾醇/有机酸

Key words

Pinelliae Rhizoma/Chemical composition/Pharmacological effect/Quality marker/Levoephedrine/Trigonelline/Glycosides/β-sitosterol/Organic acid

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基金项目

甘肃省科技计划项目(22CX8NK244)

中药材及饮片质量控制重点实验室项目(2021GSMPA-KL08)

出版年

2024
华西药学杂志
四川大学,四川省药学会

华西药学杂志

CSTPCD北大核心
影响因子:0.624
ISSN:1006-0103
参考文献量36
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