Study on the chemical constituents of Saxifraga umbellulata var.pectinate
OBJECTIVE To study the chemical constituents from the whole plants of Saxifraga umbellulata var.pectinate.METHODS The constituents were isolated and purified by silica gel,polyamide,C18 reversed phase and Sephadex LH-20 column chromatographies,and their structures were identified by NMR spectra and physical-chemical constants.RESULTS Nine compounds were isolated from the 95％ethanol extract of S.umbellulata var.pectinate and identified as(6R,7E,9R)-9-hydroxy-4,7-megastigmadien-3-one-9-O-β-D-glucopyranoside(Ⅰ),3β,5β,6α-trihydroxy-7-megastigmen-9-one-3-O-β-D-glucopyranoside(Ⅱ),betulabuside A(Ⅲ),cucurbitacin F(Ⅳ),hemsamabilinin B(Ⅴ),gallic acid(Ⅵ),kaempferitrin(Ⅶ),kaempferol 3-O-α-L-(3-O-acetyl)-rhamnopyranosyl-7-O-α-L-rhamnopyranoside(Ⅷ),and β-carotene(Ⅸ).CONCLUSION Compounds Ⅰ-Ⅴ have been isolated from genus Saxifraga for the first time.
NETL
NSTL
万方数据
