石墨炉原子吸收法测定枸橼酸铁铵中的铬元素
Determination of chromium in Ferric ammonium citrate by Graphite furnace atomic absorption spectrometry
黄俊1
作者信息
- 1. 重庆市食品药品检验检测研究院国家药品监督管理局麻醉精神药品质量监测重点实验室,重庆 401121
- 折叠
摘要
目的 采用石墨炉原子吸收光谱法测定枸橼酸铁铵中的铬(Cr)元素.方法 采用硝酸消解,灰化温度1500℃,原子化温度2300 ℃.结果 测定Cr的检出限为0.26 ng·mL-1,r为0.9990,RSD=1.85％;平均回收率为96.92％(RSD=2.77l％,n=9).结论 所用方法灵敏度高、选择性好,可用于枸橼酸铁铵中Cr的测定.
Abstract
OBJECTIVE To detect chromium in Ferric ammonium citrate by graphite furnace atomic absorption spectrometric method.METHODS Nitric acid was selected as the digestive acid.The ashing temperature was 1500 ℃,and the atomization temperature was 2300 ℃.RESULTS The method exhibited a detection limit of 0.26 ng·mL-1 with r of 0.9990.RSD of precision test was 1.85％.The average recovery was 96.92％,RSD of recovery was 2.77％(n=9).CONCLUSION The method is accurate with high sensitivity and specificity,and suitable for the determination of chromium in Ferric ammonium citrate.
关键词
石墨炉/原子吸收法/枸橼酸铁铵/铬/重金属/含量测定/原料药/缺铁性贫血Key words
Graphite furnace/Atomic absorption spectrometry/Ferric ammonium citrate/Chromium/Heavy metals/Assay/Drug substance/Iron-deficiency anemia引用本文复制引用
出版年
2024
NETL
NSTL
万方数据