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马钱子碱抗肿瘤作用的研究进展

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马钱子碱具有抗炎镇痛、调节神经系统、抗心律失常、抗血栓、促进成骨等作用.将马钱子碱用于治疗乳腺癌、肝癌、结直肠癌等疾病的研究日益增多.现综述近年来有关马钱子碱抗肿瘤作用的研究进展.
Research progress on anticancer effects of brucine
Brucine is one of the main components derived from the dried mature seeds of Strychnos nux-vomica L.and S.Prerriana A.W.Hill.Brucine has been proved possessing many effects,such as anti-inflammatory and analgesic,regulating the nervous system,anti-arrhythmia,antithrombotic,promoting osteogenesis.It has been used in the treatment of diseases including osteoarthritis,paralysis,scabies and so on.The anti-tumor effect of brucine in diseases such as breast cancer,liver cancer,colorectal cancer and other diseases has become increasingly active.The recent research progress on the antitumor effect of brucine is reviewed.

BrucineStrychnos nux-vomicaS.PrerrianaAnticancerHepatocarcinomaTriple-negative breast cancerLung cancerColon cancerMultiple myelomaResearch progress

余源、黄媚娟

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四川大学华西医院,四川成都 610041

马钱子碱 马钱 云南马钱 抗肿瘤 肝癌 三阴性乳腺癌 肺癌 结肠癌 多发性骨髓瘤 研究进展

四川大学华西医院临床研究孵化项目重点项目

2021HXFH055

2024

华西药学杂志
四川大学,四川省药学会

华西药学杂志

CSTPCD北大核心
影响因子:0.624
ISSN:1006-0103
年,卷(期):2024.39(2)
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