华西药学杂志2024,Vol.39Issue(2) :231-234.DOI:10.13375/j.cnki.wcjps.2024.02.023

马钱子碱抗肿瘤作用的研究进展

Research progress on anticancer effects of brucine

余源 黄媚娟
华西药学杂志2024,Vol.39Issue(2) :231-234.DOI:10.13375/j.cnki.wcjps.2024.02.023

马钱子碱抗肿瘤作用的研究进展

Research progress on anticancer effects of brucine

余源 1黄媚娟1
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作者信息

  • 1. 四川大学华西医院,四川成都 610041
  • 折叠

摘要

马钱子碱具有抗炎镇痛、调节神经系统、抗心律失常、抗血栓、促进成骨等作用.将马钱子碱用于治疗乳腺癌、肝癌、结直肠癌等疾病的研究日益增多.现综述近年来有关马钱子碱抗肿瘤作用的研究进展.

Abstract

Brucine is one of the main components derived from the dried mature seeds of Strychnos nux-vomica L.and S.Prerriana A.W.Hill.Brucine has been proved possessing many effects,such as anti-inflammatory and analgesic,regulating the nervous system,anti-arrhythmia,antithrombotic,promoting osteogenesis.It has been used in the treatment of diseases including osteoarthritis,paralysis,scabies and so on.The anti-tumor effect of brucine in diseases such as breast cancer,liver cancer,colorectal cancer and other diseases has become increasingly active.The recent research progress on the antitumor effect of brucine is reviewed.

关键词

马钱子碱/马钱/云南马钱/抗肿瘤/肝癌/三阴性乳腺癌/肺癌/结肠癌/多发性骨髓瘤/研究进展

Key words

Brucine/Strychnos nux-vomica/S.PrerrianaAnticancer/Hepatocarcinoma/Triple-negative breast cancer/Lung cancer/Colon cancer/Multiple myeloma/Research progress

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基金项目

四川大学华西医院临床研究孵化项目重点项目(2021HXFH055)

出版年

2024
华西药学杂志
四川大学,四川省药学会

华西药学杂志

CSTPCD北大核心
影响因子:0.624
ISSN:1006-0103
参考文献量32
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