Therapeutic effects of Shiwei Ruxiang capsules on rheumatoid arthritis rats
OBJECTIVE To explore the therapeutic effect of the Tibetan medicine Shiwei Ruxiang capsules on rheumatoid arthritis(RA)rats.METHODS A combination model of collagen-induced RA rats with cold-damp stimulation was established and the rats were given corresponding treatment.The general state of rats was observed daily,and body weight,foot-plantar thickness and ankle joint swelling were measured.28 days after administration,the mice were sacrificed and blood,joint,thymus and spleen tissues were collected for biochemical and pathological tests.RESULTS Shiwei Ruxiang capsules inhibited the levels of IL-6,IL-1β and TNF-α in serum and synovial tissues,decreased the ratio of CD4+/CD8+T cells,and improved the arthritic symptoms of RA rats.CONCLUSION Shiwei Ruxiang capsules demonstrate good therapeutic effect on RA rats.
NETL
NSTL
万方数据
