Study on the quality standard of Heracleum millefolium
OBJECTIVE To establish the quality standard of Heracleum millefolium Diels for the first time.METHODS Classical methods such as morphological identification,microscopic identification,and thin-layer chromatography were used to determine the characteristics of H.millefolium.The testing methods from the general principles of Part Four of the 2020 edition of the Chinese Pharmacopoeia were used to measure moisture content,total ash,acid-insoluble ash,and extractives in H.millefolium.The ultra-high-performance liquid chromatography method was applied to determine the content of the marker compound,rutin.RESULTS The distinguishing features of H.millefolium were significant and could be utilized as identification methods for this medicinal herb.Preliminary specifications for H.millefolium were proposed,indicating that the moisture content not exceeding 13.0％,total ash not exceeding 15.0％,acid-insoluble ash not exceeding 4.0％,extractives not less than 18.0％,and rutin content not less than 1.3％.CONCLUSION The established methods demonstrate accuracy,reproducibility and stability,providing a scientific basis for the establishment of quality standards for H.millefolium.
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