Progresses in detecting shellfish toxins with hydrophilic interaction chromatography-mass spectrometry
Shellfish toxins are toxic macromolecular compounds produced by toxic algae in the ocean.Shellfish accumulate in their body by ingesting toxic algae,which seriously threatens the health of con-sumers.In this paper,we reviewed the classification of shellfish toxins and the retention mechanism and characteristics of hydrophilic interaction chromatography(HILIC).The application of hydrophilic interaction chromatography-mass spectrometry(HILIC-MS)in determining shellfish toxins was intro-duced,and the development trend of HILIC-MS in the detection and analysis of shellfish toxins was put forward.