利用亲水作用色谱-质谱联用技术检测贝类毒素研究进展
Progresses in detecting shellfish toxins with hydrophilic interaction chromatography-mass spectrometry
郑旭颖 1孙晓杰 2李兆新 2邢丽红 2蒋万枫3
作者信息
- 1. 中国水产科学研究院黄海水产研究所,山东青岛 266071;上海海洋大学食品学院,上海 201306
- 2. 中国水产科学研究院黄海水产研究所,山东青岛 266071;农业农村部水产品质量安全风险评估实验室(青岛),山东青岛 266071
- 3. 青岛市食品药品检验研究院,山东青岛 266073
- 折叠
摘要
贝类毒素是由海洋中有毒藻类产生的有毒高分子化合物,贝类通过摄食有毒藻类在体内蓄积,严重威胁消费者健康.本文综述了贝类毒素的分类及亲水作用色谱(HILIC)的保留机理和特点.重点介绍了亲水作用色谱-质谱联用(HILIC-MS)技术在贝类毒素测定方面的应用研究进展,并提出了 HIL-IC-MS在贝类毒素检测分析方面的发展趋势.
Abstract
Shellfish toxins are toxic macromolecular compounds produced by toxic algae in the ocean.Shellfish accumulate in their body by ingesting toxic algae,which seriously threatens the health of con-sumers.In this paper,we reviewed the classification of shellfish toxins and the retention mechanism and characteristics of hydrophilic interaction chromatography(HILIC).The application of hydrophilic interaction chromatography-mass spectrometry(HILIC-MS)in determining shellfish toxins was intro-duced,and the development trend of HILIC-MS in the detection and analysis of shellfish toxins was put forward.
关键词
贝类毒素/亲水作用色谱-质谱联用(HILIC-MS)/检测Key words
shellfish toxin/hydrophilic interaction chromatography-mass spectrometry(HILIC-MS)/detection引用本文复制引用
基金项目
国家重点研发计划蓝色粮仓科技创新重点专项(2019YFD0901700)
出版年
2024
NETL
NSTL
万方数据