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利用亲水作用色谱-质谱联用技术检测贝类毒素研究进展

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贝类毒素是由海洋中有毒藻类产生的有毒高分子化合物,贝类通过摄食有毒藻类在体内蓄积,严重威胁消费者健康.本文综述了贝类毒素的分类及亲水作用色谱(HILIC)的保留机理和特点.重点介绍了亲水作用色谱-质谱联用(HILIC-MS)技术在贝类毒素测定方面的应用研究进展,并提出了 HIL-IC-MS在贝类毒素检测分析方面的发展趋势.
Progresses in detecting shellfish toxins with hydrophilic interaction chromatography-mass spectrometry
Shellfish toxins are toxic macromolecular compounds produced by toxic algae in the ocean.Shellfish accumulate in their body by ingesting toxic algae,which seriously threatens the health of con-sumers.In this paper,we reviewed the classification of shellfish toxins and the retention mechanism and characteristics of hydrophilic interaction chromatography(HILIC).The application of hydrophilic interaction chromatography-mass spectrometry(HILIC-MS)in determining shellfish toxins was intro-duced,and the development trend of HILIC-MS in the detection and analysis of shellfish toxins was put forward.

shellfish toxinhydrophilic interaction chromatography-mass spectrometry(HILIC-MS)detection

郑旭颖、孙晓杰、李兆新、邢丽红、蒋万枫

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中国水产科学研究院黄海水产研究所,山东青岛 266071

上海海洋大学食品学院,上海 201306

农业农村部水产品质量安全风险评估实验室(青岛),山东青岛 266071

青岛市食品药品检验研究院,山东青岛 266073

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贝类毒素 亲水作用色谱-质谱联用(HILIC-MS) 检测

国家重点研发计划蓝色粮仓科技创新重点专项

2019YFD0901700

2024

海洋湖沼通报
山东海洋湖沼学会

海洋湖沼通报

CSTPCD北大核心
影响因子:0.464
ISSN:1003-6482
年,卷(期):2024.46(2)
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