Consolidated bioprocessing(CBP)is considered as the most ideal form for lignocellulose conversion.Although the modification of metabolic engineering can achieve CBP based on a single strain,excessive metabolic pressure alone leads to the suboptimal transformation efficiency of strain.This article fo-cused on the interspecific division in the microbial community of degrading natural lignocellulosic to system-atically understand the interspecific division of labor and realize the rational design of CBP.The current pat-terns of interspecific division of labor were reviewed in terms of the synergistic hydrolysis of substrate,the cross-feeding of nutritional factors,and the restriction of"sugar cheaters".The application of interspecific division of labor in lignocellulose conversion,the challenges and development directions of studying inter-specific division in microbial communities of natural lignocellulose were introduced.It will provide principles for designing the construction of a microbial community with consolidated bioprocessing to promote the effi-cient biotransformation of lignocellulose.
microbial communitiesinterspecific division of laborlignocellulose conversionconsoli-dated bioprocessingsynthetic consortium
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