Research Progress of Transition Metal-catalyzed Halosilane Conversion to Construct Si—C Bond Reaction
Organosilicon compounds are extensively utilized in organic synthesis,and the development of efficient methodologies for incorporating silicon atoms into molecules has attracted significant attention.This paper provides a comprehensive review of research conducted over the past two decades on the construction of Si—C bond,focusing on three key aspects:form reagent promotion reactions,silyl-Heck and silyl-Negishi reactions,as well as cross-coupling reactions catalyzed by transition metals.It was observed that the high bonding energy associated with Si—C bonds poses a major challenge when utilizing halosilanes for their construction.Consequently,expanding the substrate range of chlorosilanes and exploring more favorable reaction conditions will be topics warranting further discussion in future studies.
transition metalhalosilaneSi—C bond synthesisSi—X bond formation
万方数据
维普
