Objective To observe clinical efficacy of bortezomib as the main chemotherapy regimen in the treatmwent of patients with initially treated multiple myeloma.Methods 43 patients with multiple myeloma were selected and randomly divided into the observation group(20 cases)and the control group(23 cases).The observation group received bortezomib as the main chemotherapy regimen,the control group received traditional treatment.The treatment lasted 4 courses.The changes of overall response rate,erythrocyte sedimentation rate,globulin and bone marrow plasma cells were compared between the two groups before and after treatment.Results After 4 courses of chemotherapy,the overall response rate in the observation group was significantly higher than that in the control group(P<0.05).The globulin,erythrocyte sedimentation rate,plasma cell ratio in the observation group was significantly higher than those in the control group(P<0.05).Conclusion Compared with the traditional treatment regimen,bortezomib as the main chemotherapy regimen can improve the curative effect of multiple myeloma.
维普
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