Dietary patterns and cardiovascular disease among adults in Guizhou Province:a cohort study
Objective To explore the relationship between dietary patterns and cardiovascular disease(CVD),so as to provide evidence for the prevention of CVD.Methods Based on the natural population cohort established in November 2010,a total of 9 280 permanent residents over 18 years old in 12 counties and districts of Guizhou Province were selected by the method of stratified cluster sampling for baseline investigation,those participants received followed up from December 19th 2016 to June 1th 2020.Ultimately,7 897 individual were eligible by successfully followed-up with complete information at baseline and follow-up for the analysis.Dietary information was obtained by the semi-quantitative food frequency method and dietary patterns were sorted with exploratory factor analysis.Cox proportional risk regression model was conducted to analyze the relationship between dietary patterns and CVD,then the hazard ratio(HR)and corresponding 95%confidence interval were calculated.Results The average age of the subjects was(44.46±15.14)years old,during a median duration of 6.58 years(55 698.80 person-years)of follow-up,221 new case of CVD were found,the incidence rate of CVD was 3.97/1 000 person-years.Five main dietary patterns determined via factor analysis,named oil and salt pattern,protein pattern,sweet pattern,grain-vegetable pattern,aquatic product pattern,respectively.In the Cox proportional risk regression model,after adjusting other factors,the high level of oil and salt pattern was significantly associated with increasing the risk of CVD(HR=1.44,95%CI:1.02-2.02,P<0.05),medium(HR=1.47,95%CI:1.04-2.06,P<0.05)and high level(HR=1.66,95%CI:1.17-2.36,P<0.05)of sweet pattern statistically argument occurrence of CVD compared with the low level of such patterns.Conclusions Oil and salt pattern and sweet pattern can increase the risk of CVD,reducing the intake of fat,salt and sugary foods can prevent and control the occurrence of CVD.
Cardiovascular diseaseDietary patternsCohort study