首页|贵州省成年人群膳食模式与心血管疾病发病关系的队列研究

贵州省成年人群膳食模式与心血管疾病发病关系的队列研究

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目的 分析不同膳食模式与心血管疾病(cardiovasculardisease,CVD)发病的关系,为CVD的防控提供参考依据.方法 基于2010年11月建立的贵州省自然人群队列,采取分层整群抽样的方法抽取贵州省12个县(市、区)的≥18岁常住居民9 280人开展基线调查,于2016年12月19日—2020年6月1日对人群进行随访,将完成随访且基线信息和随访结局完整的7 897人纳入分析.采用半定量食物频率法获得人群膳食信息,通过探索性因子分析确定膳食模式,使用Cox比例风险回归模型计算队列人群不同膳食模式和CVD发生的HR值和95%CI.结果 研究对象基线年龄为(44.46±15.14)岁,累计随访55 698.80人年,中位随访时间6.58年,随访期间221人发生CVD,发病密度为3.97/1 000人年.因子分析确定了油盐模式、蛋白模式、甜食模式、谷蔬模式、水产品模式.调整其他因素后,与各模式的低水平组相比,高水平油盐模式(HR=1.44,95%CI:1.02-2.02,P<0.05)、中水平甜食模式(HR=1.47,95%CI:1.04-2.06,P<0.05)、高水平甜食模式(HR=1.66,95%CI:1.17-2.36,P<0.05)与CVD的发生呈正相关.结论 油盐膳食模式和甜食膳食模式增加人群CVD的发病风险,限制脂肪、盐及含糖食品的摄人可预防和控制CVD的发生.
Dietary patterns and cardiovascular disease among adults in Guizhou Province:a cohort study
Objective To explore the relationship between dietary patterns and cardiovascular disease(CVD),so as to provide evidence for the prevention of CVD.Methods Based on the natural population cohort established in November 2010,a total of 9 280 permanent residents over 18 years old in 12 counties and districts of Guizhou Province were selected by the method of stratified cluster sampling for baseline investigation,those participants received followed up from December 19th 2016 to June 1th 2020.Ultimately,7 897 individual were eligible by successfully followed-up with complete information at baseline and follow-up for the analysis.Dietary information was obtained by the semi-quantitative food frequency method and dietary patterns were sorted with exploratory factor analysis.Cox proportional risk regression model was conducted to analyze the relationship between dietary patterns and CVD,then the hazard ratio(HR)and corresponding 95%confidence interval were calculated.Results The average age of the subjects was(44.46±15.14)years old,during a median duration of 6.58 years(55 698.80 person-years)of follow-up,221 new case of CVD were found,the incidence rate of CVD was 3.97/1 000 person-years.Five main dietary patterns determined via factor analysis,named oil and salt pattern,protein pattern,sweet pattern,grain-vegetable pattern,aquatic product pattern,respectively.In the Cox proportional risk regression model,after adjusting other factors,the high level of oil and salt pattern was significantly associated with increasing the risk of CVD(HR=1.44,95%CI:1.02-2.02,P<0.05),medium(HR=1.47,95%CI:1.04-2.06,P<0.05)and high level(HR=1.66,95%CI:1.17-2.36,P<0.05)of sweet pattern statistically argument occurrence of CVD compared with the low level of such patterns.Conclusions Oil and salt pattern and sweet pattern can increase the risk of CVD,reducing the intake of fat,salt and sugary foods can prevent and control the occurrence of CVD.

Cardiovascular diseaseDietary patternsCohort study

张骥、周婕、余丽莎、王艺颖、吴延莉、李雪娇、刘涛

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贵州省疾病预防控制中心慢性非传染性疾病防治研究所监测科,贵阳 550004

心血管疾病 膳食模式 队列研究

贵州省科技支撑计划

黔科合支撑[2018]2819

2024

中华疾病控制杂志
中华预防医学会 安徽医科大学

中华疾病控制杂志

CSTPCD北大核心
影响因子:1.862
ISSN:1674-3679
年,卷(期):2024.28(2)
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