Association between different metabolic types of obesity and glycemic control among community type 2 diabetes patients in Nanjing
Objective To investigate the distribution characteristics and glycemic control of type 2 diabetes patients with different metabolic types and obesity in community in Nanjing.Methods From April to June 2021,multi-stage stratified cluster random sampling method was adopted to recruit type 2 diabetes patients in 12 districts of Nanjing,questionnaire responses,physical examinations and clinical indicators were gathered.According to their metabolic and BMI,the population was divided into metabolically healthy and normal weight(MHNW),metabolically unhealthy but normal weight(MUHNW),metabolically healthy obese(MHO),and metabolically abnormal obese(MAO).Logistic regression was used for multivariate analysis.Results A total of 1 389 subjects were included,with an average age of(65.14±7.71)years old,598 males(43.05%),among which MHNW,MUHNW,MHO,MAO were 21.31%,22.97%,7.85%and 47.87%.The older the age,the higher the incidence of MUHNW and MAO;The proportion of MUHNW in women and patients with diabetes course ≥5 years was higher.The control up to standard rates of fasting blood glucose(FPG)and hemoglobinA1c(HbA1c)among the subjects were 44.92%and 48.88%,respectively.The results of multivariate analysis showed that the incidence of FPG control failure in MAO patients was 1.525 times higher than that in MHNW(OR=1.525,95%CI:1.148-2.025,P=0.004);The incidence of HbAlc control failure in MAO patients was1.516 times higher than that in MHNW patients(OR=1.516,95%CI:1.140-2.016,P=0.004),with statistically significant(P<0.05).Conclusions There are more type 2 diabetes patients with MUHNW and MAO in Nanjing,and the type 2 diabetes patients with MAO have poor glycemic con-trol.Early identification and classified intervention should be carried out for type 2 diabetes patients with different obesity subgroups to effectively control blood glucose,and to prevent and control complications of diabetes.
Type 2 diabetesMetabolic typeObesityGlycemic control