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广州市6~12岁儿童糖代谢异常流行状况及其影响因素

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目的 了解广州市6~12岁儿童空腹血糖(fasting plasma glucose,FPG)水平和糖代谢异常现状及其影响因素.方法 采用分层整群随机抽样方法,在广州市抽取5所小学共4 690名6~12岁儿童进行问卷调查、体格检查和FPG检测.根据FPG值对儿童糖尿病(diabetes mellitus,DM)(FPG≥7.0 mmol/L)、空腹血糖受损(impaired fasting glucose,IFG)(6.1 mmol/L≤FPG<7.0 mmol/L)和糖代谢异常(FPG≥6.1 mmol/L)进行筛查.采用多因素线性回归分析模型和多因素logistic回归分析模型分析儿童FPG和糖代谢异常的影响因素.结果 广州市6~12岁儿童FPG平均水平为(5..16±0.34)mmol/L,糖代谢异常率、IFG和DM检出率分别为0.79%、0.64%和0.15%.多因素线性回归分析模型结果显示男童(β=0.161,95%CI:0.089~0.135,P<0.001)、9~12岁儿童(9~<11岁:β=0.071,95%CI:0.025~0.075,P<0.001;11~12 岁:β=0.090,95%CI:0.056~0.126,P<0.001)、腹型肥胖儿童(β=0.042,95%CI:0.009~0.078,P=0.013)FPG 水平较高.多因素 logistic回归分析模型分析结果腹型肥胖(β=1.576,OR=4.838,95%CI:2.200~10.638,P<0.001)、未每天吃早餐的儿童(β=1.158,OR=3.184,95%CI:1.069~9.484,P=0.038)糖代谢异常风险较高.结论 广州市6~12岁儿童糖代谢异常率偏低,腹型肥胖、未每天吃早餐是儿童糖代谢异常的危险因素.
The prevalence of abnormal glucose metabolism and its associated factors in children aged 6-12 years in Guangzhou
Objective To investigate the prevalence of abnormal glucose metabolism and its as-sociated risk factors in children aged 6-12 years in Guangzhou,China.Methods We adopted the meth-od of stratified cluster random sampling to recruit a total of 4 690 children aged 6-12 from 5 primary schools in Guangzhou.All participants completed the questionnaire survey,physical examination,and fasting plasma glucose(FPG)detection.Children were screened for diabetes mellitus(DM)(FPG≥7.0 mmol/L),impaired fasting glucose(IFG)(6.1 mmol/L ≤FPG<7.0 mmol/L),and abnormal glucose metabolism(FPG ≥6.1 mmol/L)based on FPG.Multiple linear regression and multiple logistic regression were used to analyze the risk factors of FPG and abnormal glucose metabolism.Results The average FPG of children was(5.16±0.34)mmol/L.The prevalence of abnormal glucose metabolism,IFG,and DM were 0.79%,0.64%,and 0.15%,respectively.Boys(β=0.161,95%CI:0.089-0.135,P<0.001),9-12 years children(9-<11 years old:β=0.071,95%CI:0.025-0.075,P<0.001;11-12 years old:β=0.090,95%CI:0.056-0.126,P<0.001),and children with abdominal obesity(β=0.042,95%CI:0.009-0.078,P=0.013)had higher FPG levels.Children with abdominal obesity(β=1.576,OR=4.838,95%CI:2.200-10.638,P<0.001)and children who did not eat breakfast every day(β=1.158,OR=3.184,95%CI:1.069-9.484,P=0.038)had a higher risk of abnormal glucose metabolism.Conclusions The prevalence of abnormal glucose metabolism in children aged 6-12 years in Guangzhou is low.Abdominal obesity and not eating breakfast every day are risk factors of abnormal glucose metabolism in children.

Fasting plasma glucoseAbnormal glucose metabolismDiabetes mellitusInfluencing factors

普迎琦、桂曌环、黄闪、张羽珊、陈亚军

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中山大学公共卫生学院妇幼卫生学系,广州 510080

空腹血糖 糖代谢异常 糖尿病 影响因素

国家自然科学基金

81673193

2024

中华疾病控制杂志
中华预防医学会 安徽医科大学

中华疾病控制杂志

CSTPCD北大核心
影响因子:1.862
ISSN:1674-3679
年,卷(期):2024.28(2)
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