The prevalence of abnormal glucose metabolism and its associated factors in children aged 6-12 years in Guangzhou
Objective To investigate the prevalence of abnormal glucose metabolism and its as-sociated risk factors in children aged 6-12 years in Guangzhou,China.Methods We adopted the meth-od of stratified cluster random sampling to recruit a total of 4 690 children aged 6-12 from 5 primary schools in Guangzhou.All participants completed the questionnaire survey,physical examination,and fasting plasma glucose(FPG)detection.Children were screened for diabetes mellitus(DM)(FPG≥7.0 mmol/L),impaired fasting glucose(IFG)(6.1 mmol/L ≤FPG<7.0 mmol/L),and abnormal glucose metabolism(FPG ≥6.1 mmol/L)based on FPG.Multiple linear regression and multiple logistic regression were used to analyze the risk factors of FPG and abnormal glucose metabolism.Results The average FPG of children was(5.16±0.34)mmol/L.The prevalence of abnormal glucose metabolism,IFG,and DM were 0.79%,0.64%,and 0.15%,respectively.Boys(β=0.161,95%CI:0.089-0.135,P<0.001),9-12 years children(9-<11 years old:β=0.071,95%CI:0.025-0.075,P<0.001;11-12 years old:β=0.090,95%CI:0.056-0.126,P<0.001),and children with abdominal obesity(β=0.042,95%CI:0.009-0.078,P=0.013)had higher FPG levels.Children with abdominal obesity(β=1.576,OR=4.838,95%CI:2.200-10.638,P<0.001)and children who did not eat breakfast every day(β=1.158,OR=3.184,95%CI:1.069-9.484,P=0.038)had a higher risk of abnormal glucose metabolism.Conclusions The prevalence of abnormal glucose metabolism in children aged 6-12 years in Guangzhou is low.Abdominal obesity and not eating breakfast every day are risk factors of abnormal glucose metabolism in children.