Self-efficacy as a moderator in relationship between medication adherence and quality of life among patients with type 2 diabetes
Objective To explore the association between medication adherence and quality of life among patients with type 2 diabetes and the moderating role of self-efficacy on the relationship above.Methods A total of 728 eligible patients with type 2 diabetes were included and data were collected based on the 8-item Morisky medication adherence scale(MMAS-8),diabetes specific quality of life scale(DSQL),and the self-administered diabetes self-efficacy scale.Multiple linear regression models were established to analyze the associations between medication adherence and quality of life and further explored the moderating effect of self-efficacy.Results Among them,125 patients(17.2%)had good medication adherence.Compared with baseline,scores of DSQL social dimension increased significantly after 9 months of follow-up(t=-3.668,P=0.001).Medication adherence was negatively associated with baseline total DSQL score(β=-0.161,P<0.001)and month 9 total DSQL score(β=-0.148,P=0.002).Higher self-efficacy enhanced the relationship between medication adherence and DSQL cure dimension(β=0.150,P=0.010)and overall DSQL(β=0.110,P=0.044)at month 9.Conclusions Medication adherence is significantly associated with short-term future quality of life of patients with type 2 diabetes.Improving self-efficacy enhances the positive effect of medication adherence on quality of life,especially on the cure dimension of life quality.
Medication adherenceQuality of lifeSelf-efficacyType 2 diabetes