A cohort study of the effect of sleep duration on possible sarcopenia in rural middle-aged and eld-erly people in China
Objective To explore the effect of sleep duration on the risk of possible sarcopenia in rural middle-aged and elderly adults(≥45 years)in order to reduce the incidence of possible sarcopenia.Methods The cohort study was conducted base on the Chinese health and retirement longitudinal study(CHARLS).Possible sarcopenia was identified by measuring grip strength and five repetitions of sitting-up time.A total of 7 075 participants of middle-aged and elderly adults aged≥45 years without possible sarcopenia in 2011 and 2013 were used as baseline data,and were followed up until 2015.Cox proportional risk model was used to explore the association between sleep duration and the risk of possible sarcopenia in rural middle-aged and elderly people.Results Compared to rural middle-aged and elderly adults with sleep duration of 8-＜9 hours,those with sleep duration less than 6 hours,6-＜7 hours,7-＜8 hours and more than 9 hours had an increased risk of possible sarcopenia by 22％(HR=1.22,95％CI:1.07-1.39,P=0.003),17％(HR=1.17,95％CI:1.01-1.35,P=0.037),18％(HR=1.18,95％CI:1.02-1.35,P=0.022)and 16％(HR=1.16,95％CI:1.02-1.33,P=0.028)respectively.Trend test showed that the risk of possible sarcopenia increased with the shortening of sleep time(＜9 h),and there was a dose-response relationship(P＜0.001).Among participants aged 45-＜60 years,compared with sleep duration of 8-＜9 hours,the risk of possible sarcopenia with sleep duration less than 6 hours,6-＜7 hours and 7-＜8 hours was increased by 21％(HR=1.21,95％CI:1.01-1.46,P=0.041),23％(HR=1.23,95％CI:1.02-1.48,P=0.033)and 30％(HR=1.30,95％CI:1.08-1.56,P=0.005),respectively.Compared with sleep duration of 8-＜9 hours,short sleep duration(＜6 h)was associated with a 27％increased risk of possible sarcopenia in females(HR=1.27,95％CI:1.06-1.52,P=0.010),and long sleep duration(≥9 h)was associated with a 21％increased risk of possible sarcopenia in males(HR=1.21,95％CI:1.01-1.46,P=0.045).Conclusions The shorter and longer sleep duration among rural middle-aged and elderly were associated with an increased risk of possible sarcopenia,and there existed age differences.Optimizing sleep duration may prevent the occurrence and development of sarcopenia.
Possible sarcopeniaSleep durationCohort studyMiddle-aged and elderly adultsRural
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