Analysis of the risk factors of coronary heart disease in population at high cardiovascular risk in Inner Mongolia
Objective To explore the related risk factors of coronary heart disease(CHD)in the population at high risk of cardiovascular disease in Inner Mongolia,and to provide scientific basis for the development of prevention and treatment strategies for CHD in Inner Mongolia.Methods This study was a prospective cohort study,the study population was selected by multi-stage stratified cluster sampling method.A survey was conducted in six cities in Inner Mongolia region from December 2015,and the follow-up survey was conducted once a year until December 2021.The baseline survey included general information,disease and treatment history,physical examination and laboratory tests.The follow-up survey included cardiovascular health status and clinical endpoint events.Cox regression model was used to analyze the risk factors of CHD.Results A total of 37 726 subjects were finally included in this study,multivariate Cox regression analysis showed that:increasing age(HR>1.00,P<0.001),smoking(HR=1.20,P<0.001),drinking(HR=1.41,P<0.001),overweight or obesity(HR=1.19,P<0.001),hypertension(HR=1.41,P<0.001),diabetes(HR=1.22,P<0.001)were dyslipidemia(HR=2.20,P<0.001)were risk factors for CHD.In contrast,high education level(HR<1.00,P<0.001)and non-heavy physical labor type(HR<1.00,P<0.001)were protective factors for CHD.Con-clusions In Inner Mongolia,increasing age,smoking,drinking,dyslipidemia,hypertension,diabetes,overweight or obesity are risk factors for CHD,high education level and non-heavy physical labor type are protective factors for CHD.
Coronary heart diseaseInfluencing factorsHigh-risk populationCohort study