Differential prevalence and correlates of anemia among newly diagnosed versus formerly reported HIV-infected persons in Taizhou City
Objective This study aims to explore and draw comparison in influencing factors between newly diagnosed and formerly reported HIV-infected persons in Taizhou City.The findings provide scientific evidence for improving preventative measures and treatment for anemia in HIV-infected individuals.Methods A total of 2 756 HIV-infected individuals from the Comparative HIV and aging research in Taizhou(CHART)were recruited in Taizhou,Zhejiang Province,include 620 newly diagnosed cases and 2 136 formerly reported cases.Logistic regression models were used to analyze the factors influencing anemia among HIV-infected individuals and draw comparion in influencing factors between newly diagnosed and formerly reported HIV-infected persons.Results Among the 2 756 HIV-infected individuals surveyed,the prevalence of anemia was 18.7％(516/2,756).Among the 620 newly diagnosed HIV cases,the prevalence of anemia was 23.6％(146/620),while among the 2 136 formerly reported HIV cases,the prevalence of anemia was 17.3％(370/2 136).Multivariable logistic regression analysis showed that both newly diagnosed and previously infected individuals shared gender and CD4 count as influencing factors for anemia,in addition to which,among newly diagnosed cases,other influencing factors included underweight(OR=2.88,95％CI:1.56-5.33,P=0.001),overweight or obesity(OR=0.47,95％CI:0.28-0.81,P=0.006),history of tuberculosis(OR=11.16,95％CI:1.55-80.27,P=0.017),and mild renal insufficiency(OR=1.87,95％CI:1.07-3.25,P=0.027).Among Previously infected individuals,the influencing factors included the age group of 45-59 years(OR=2.05,95％CI:1.30～3.24,P=0.002),age ≥60 years(OR=3.48,95％CI:2.08～5.83,P＜0.001),education level of high school or above(OR=0.62,95％CI:0.44-0.90,P=0.010),diabetes(OR=1.60,95％CI:1.04-2.47,P=0.034),and hypercholesterolemia(OR=0.73,95％CI:0.55-0.96,P=0.023).Conclusions The prevalence of anemia among HIV-infected individuals in Taizhou City is relatively lower compared to other HIV-infected populations in China during the same period.Aside from gender and CD4 cell count,newly diagnosed and formerly reported HIV cases differ in the factors influencing anemia.Therefore,precise interventions of anemia among HIV-infected individuals should be emphasized in the prevention,screening,and treatment of anemia.
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