山西省东南部地区机构养老人群高钾血症患病率及影响因素
Analysis of prevalence and influencing factors of hyperkalemia among people in elderly care institutions in southeastern Shanxi
段培芬 1原建慧 1韩艳波 1翟艳丽 1冯向先1
作者信息
- 1. 长治医学院公共卫生与预防医学系,长治 046000
- 折叠
摘要
目的 了解山西省东南部地区机构养老人群高钾血症的患病率及影响因素.方法 采用随机整群抽样方法于2017年9-11月选取山西省东南部地区16家养老机构人群进行问卷调查,并采集外周血进行实验室检查.采用logistic回归分析模型分析高钾血症的影响因素.结果 共纳入研究对象523人,平均年龄为(66.20±8.61)岁;平均血钾浓度为(4.50±0.45)mmol/L,高钾血症(血钾＞5.0 mmol/L)患病率为 13.95％(95％CI:11.02％～16.93％).Logistic 回归分析模型分析结果显示随着肾小球滤过率(estimated glomerular filtration rate,eGFR)的降低,高钾血症发生风险升高(x2=8.189,P=0.017),与 eGFR＞90 mL/(min·1.73m2)相比,60～90 mL/(min· 1.73m2)与＜60 mL/(min·1.73m2)高钾血症发生风险分别为4.11倍(OR=4.11,95％CI:1.06～16.01,P=0.042)和 6.04倍(OR=6.04,95％CI:1.64～22.17,P=0.007).结论 山西省东南部地区机构养老人群中高钾血症患病率较高,eGFR低水平为高钾血症发生的危险因素.
Abstract
Objective To examine the prevalence and factors associated with hyperkalemia among the elderly residing in care facilities in the southeastern area of Shanxi province.Methods A questionnaire survey was carried out on individuals from 16 care institutions in the southeastern province of Shanxi between September and November,2017.A random cluster sampling method was employed to select subjects.In addition,peripheral blood samples were collected for laboratory examination.The analysis of hyperkalemia was conducted using logistic regression to determine the contributing factors.Results A total of 523 individuals were included in this study[average age:(66.20±8.61)years old],and the average serum potassium concentration was(4.50±0.45)mmol/L.The prevalence of hyperkalemia(＞5.0 mmol/L)was 13.95％(95％CI:11.02％-16.93％).Logistic regression analysis showed that the risk of hyperkalemia increased with a decreasing estimated glomerular filtration rate(eGFR)(x2=8.189,P=0.017).Compared with eGFR＞90 ml/(min·1.73m2),the risk of hyperkalemia was 4.11 times with eGFR 60-90 mL/(min·1.73m2)(OR=4.11,95％CI:1.06-16.01,P=0.042)and 6.04 times with eGFR＜60 mL/(min·1.73m2)(OR=6.04,95％CI:1.64-22.17,P=0.007).Conclusions The prevalence of hyperkalemia is higher in the institutionalized elderly population,and the lower level of eGFR is a risk factor for hyperkalemia.
关键词
高钾血症/患病率/影响因素Key words
Hyperkalemia/Morbidity rate/Influencing factors引用本文复制引用
基金项目
国家重点研发计划(2016YFC1300200-3)
出版年
2024
NETL
NSTL
万方数据