Epidemiological analysis on hepatitis E in Anhui Province from 2013 to 2022
Objective To analyze the epidemiological characteristics of viral hepatitis E(HE)in Anhui Province from 2013 to 2022,providing a scientific basis for the prevention and control of HE.Methods HE case report information in Anhui Province from 2013 to 2022 were collected through the Chinese Center for Disease Control and Prevention Information System for Infectious Disease Reporting.A descriptive analysis of the epidemic characteristics of HEE cases was conducted,and Joinpoint regression analyswas was used to study the temporal trends in the reported incidence of HE.Results Between 2013 and 2022,a total of 15 465 cases of HE were reported in Anhui Province,with an average annual reported incidence rate of 2.52 per 100 000.According to the Joinpoint regression model analysis,the average annual reported incidence rate of HE showed two-phase fluctuations during 2013-2022,with a turning point in 2020.From 2013 to 2020,there was a decreasing trend with an annual percent change(APC)of-6.86％(P=0.005),while from 2020 to 2022,there was a rebound with an APC of 18.33％(P=0.183).In terms of the distribution of cases,a total of 6 663 cases were reported from January to April,accounting for the highest proportion(43.08％);cases were reported in all 16 cities in Anhui Province,with the top three annual average reported incidence rates being in Bengbu City(6.70 per 100 000),Huainan City(6.28 per 100 000),and Suzhou City(4.75 per 100 000),and there was a statistically significant difference in reported incidence rates among regions(x2=6 792.45,P＜0.001);there were more male cases than female cases,with a male-to-female ratio of 2.53:1.00;cases were mainly in middle-aged and elderly people,with 60.7％of cases concentrated in the 45-＜70 age group;the main occupation was farmers,accounting for 61.05％.Conclusions The average annual reported incidence rate of HEin Anhui Province shows an overall fluctuating downward trend from 2013 to 2022,but there has been a slight increase in the past two years.The overall prevention and control of HE should not be underestimated.In the future,HE popularization should be actively carried out in key groups such as middle-aged and elderly people and farmers.Strengthening health interventions and prevention and control efforts for HE during the high-incidence seasons is also crucial.
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