Objective To analyze the epidemiological and etiological characteristics of influenza in Qingdao City from 2018 to 2022 and to summarize the epidemic patterns.The findings will provide a scientific basis for the prevention and control of influenza.Methods Descriptive epidemiological methods were used to analyze the epidemiological characteristics of influenza in Qingdao City from 2018 to 2022.Excel 2019 software and SPSS 21.0 software were utilized for organizing and analyzing the data.Results From 2018 to 2022,a total of 292 912 influenza-like illness(ILI)cases were reported in Qingdao City,and the average ILI%was 8.54%.There was a statistically significant difference in ILI%between years(x2=10 565.926,P<0.001).The proportion of ILI in the 0-<5 age group was the highest(49.22%),while the proportion in the 15-<25 age group was the lowest(5.80%).The influenza epidemic exhibits high seasonality,with the peak occurring in winter and spring,and fluctuating in summer after 2021.A total of 11 437 swab samples were tested,of which 1 206 samples tested positive for nucleic acid,resulting in a positive rate of 10.54%.The age group of 5-14 years had the highest positive rate of influ-enza virus(13.73%),followed by the 25-<60 age group(10.96%).The positive rate of the influenza virus varied significantly among different age groups(x2=60.599,P<0.001).In Qingdao City,the predominant influenza strains included seasonal H3,new A H1 and B Victoria lineage viruses,with the dominant strains varying from year to year.Conclusions Based on the influenza epidemic situation in Qingdao City,it is recommended to implement prevention and control measures,such as surveillance and early warning,before the winter and spring seasons.Meanwhile,surveillance of influenza during the sum-mer should be intensified,and prevention and control strategies should be promptly adjusted.