Systematic review of the incidence and risk factors of hypertension among HIV-positive individuals
Objective To systematically review the incidence density and influencing factors of hypertension in HIV positive people in order to explore the potential mechanisms of hypertension in HIV positive individuals.Methods We search literature related to incident hypertension among HIV-positive individuals through CNKI,Wanfang,PubMed,EMbase,Web of Science and Medline,databases and the basic information,incidence density and risk factors were extracted.Results A total of 20 studies were included,comprising 5 from North America,5 from Africa,4 from Asia,2 from Europe,and 4 from multicenter studies.The incidence density of hypertension in HIV-positive individuals ranged from 26.0 to 320.1 per 1 000 person-years.The risk factors of incident hypertension in HIV-positive individuals include traditional risk factors such as age,gender,race,BMI and abdominal obesity,diabetes,kidney disease,dyslipidemia,etc.HIV-specific factors included time of HIV infection,duration of antiviral therapy(ART),and antiviral drugs.Conclusions The incidence density of hypertension is relatively high among HIV-positive individuals,and the geographical variations are particularly pronounced.The contribution of traditional risk factors to incident hypertension among HIV-positive individuals is well established,underscoring the importance of implementing comprehensive strategies and interventions for primary prevention within this population's lifetstyles.However,the role of HIV and ART-related risk factors in hypertension remains unclear,and prospective studies are needed to better elucidate the epidemiology of hypertension in HIV-positive individuals.
Human immunodeficiency virus positiveHypertensionIncidence density
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NSTL
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