目的 分析长沙市2016-2020年干旱事件发生情况及肠道传染病流行特点,多尺度评价干旱对肠道传染病的影响,为预防干旱期间肠道传染病的发生制定科学防控方案提供依据.方法 收集长沙市2016-2020年肠道传染病发病人数资料和同期气象资料,采用Wilcoxon秩和检验比较肠道传染病日发病率变化,确定干旱相关敏感性肠道传染病;应用互相关函数初步分析肠道传染病发病相对于干旱事件的最佳滞后期;建立基于时间序列的分布滞后非线性模型,比较分析不同干旱程度对不同滞后期肠道传染病发病率的影响.结果 非干旱日与干旱日的其他感染性腹泻的发病率有差异且差异有统计学意义(Z=-2.108,P=0.035),互相关函数分析显示干旱事件与其他感染性腹泻r在d 3达到最大值(r=0.261).分布滞后非线性模型结果显示干旱期间其他感染性腹泻的单日发病风险在d 2最高(RR=1.034,95%CI:0.971~1.101),累积发病风险在 d 14 最高(RR=1.032,95%CI:0.995~1.070),0~14 d 的累积 RR 为 1.235(95%CI:1.091~1.398),2D等高线图显示随着干旱等级的增加,发病风险和影响的持续时间也会增加.结论 其他感染性腹泻是长沙市干旱敏感性肠道传染病,随着干旱等级的增加,其他感染性腹泻的发病风险增加,重旱影响的持续时间最长.
Screening and quantitative assessment of drought-sensitive intestinal infectious diseases in Changsha from 2016 to 2020
Objective To analyze the occurrence of drought events and the epidemic characteristics of intestinal infectious diseases in Changsha from 2016 to 2020,and the impact of drought on intestinal infectious diseases was evaluated at a multiple scale,so as to provide a basis for formulating scientific prevention and control plans for the prevention of intestinal infectious diseases during drought.Methods The data of the incidence of enteric infectious diseases and meteorological data during the period from 2016 to 2020 in Changsha were collected.The Wilcoxon rank sum test was used to compare the changes in the daily incidence of intestinal infectious diseases,and to determine the sensitivity of drought related intestinal infectious diseases.The cross-correlation function was used to preliminarily analyze the optimal lag period of the incidence of intestinal infectious diseases.A distributed lag nonlinear model based on time series was established to compare and analyze the effects of different levels of drought on the incidence of intestinal infectious diseases at different lag days.es between non-drought days and drought days(Z=-2.108,P=0.035).Correlation analysis revealed that the correlation coefficients be-tween drought events and OID reached their peak on the third day(r=0.261).The distributed lag non-linear model indicated that the daily risk of infectious diarrhea diseases(IDD)was highest on the second day(RR=1.034,95%CI:0.971-1.101),while the cumulative risk peaked on the 14th day(RR=1.032,95%CI:0.995-1.070),with a cumulative RR of 1.235(95%CI:1.091-1.398)from day 0 to day 14,respectively.The 2Dcontour plots demonstrated that the risk of onset and the duration of effects increased with higher drought severity.Conclusions Other infectious diarrhea is a drought sensitive in-testinal infectious disease in Changsha.The risk of OID increased with the increase of drought severity,and the impact of severe drought last the longest.
DroughtIntestinal infectious diseasesDistributed lag non-linear modelHysteresis effect