Influencing factors of thyroid volume in children aged 6-12 years in Gansu Province and compari-son of different thyroid volume correction methods
Objective To analyze the influencing factors of thyroid volume at children aged 6-12 years in Gansu Province,and to explore the appropriate correction method of thyroid volume.Methods Based on the results of the 2019 iodine deficiency disease monitoring in Gansu Province,Liangzhou District of Wuwei City and Kongtong District of Pingliang City,where iodine nutrition is appropriate,were selected as survey sites.A multi-stage stratified sampling method was used to extract non-residential chil-dren aged 6-12 years(with balanced regional and gender ratio).The height,weight,thyroid volume,urinary iodine and salt iodine in their families were measured.The influencing factors of thyroid volume in children were analyzed.The thyroid volume correction effects of body mass volume index(BMIV),body surface area volume index(BSAV),weight height volume index(WHVI),height volume index(WHVI),height volume index1(HVI1)and height volume index2(HVI2)were compared.Results Thyroid volume was not statistically significant when children of different genders(Z=-0.837,P=0.403).Spearman rank correlation analysis showed that height,body weight,BMI,body surface area(BSA),age,urinary iodine were positively correlated with thyroid volume(P＜0.001).Among them,BSA had the strongest correlation with thyroid volume(r=0.787).Quantile regression analysis showed that age and BSA had significant effects on the overall distribution of thyroid volume.Spearman rank correlation analysis of height,weight and corrected thyroid volume showed that BSAV could eliminate the influence of height and weight on thyroid volume to the greatest extent.Conclusions Age and BSA significantly affected thyroid volume.BSAV has a good correction effect on children's thyroid volume,and it is recommended to be used as an evaluation index of children's thyroid volume.
万方数据
维普
