As the aging of the population intensifies and the spectrum of diseases in the popula-tion changes,the complexity of multimorbidities of chronic diseases is increasing.Clarifying the progres-sion patterns of multimorbidities over time will provide points for further research.This study analyzes the concepts related to chronic disease multimorbidity trajectories,systematically reviews the literature visualization,and summarizes the methodological advances and research findings from three research perspectives:variable-centered,individual-centered,and disease diagnosis-centered.The development of chronic disease multimorbidity trajectory research will provide evidence to early detect disease risks,implement interventions,delay and control disease progression,and have important reference significance in identifying the mechanisms of multimorbidity occurrence and optimizing health resource allocation.
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