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2017-2022年青海省新报告HIV/AIDS病例晚发现状况及影响因素分析

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目的 分析2017-2022年青海省新报告人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染者和艾滋病(acquired immune deficiency syndrome,AIDS)患者(简称 HIV/AIDS)病例晚发现状况及相关影响因素,为制定青海省HIV/AIDS病例早发现策略提供依据.方法 从艾滋病综合防治信息管理系统中下载2017-2022年新报告的、现住址为青海省的HIV/AIDS数据,描述晚发现病例的基本人口学特征,并采用单因素分析和多因素logistic回归分析模型分析晚发现的影响因素.结果 2017-2022年青海省新报告HIV/AIDS病例共计2 299例,其中晚发现病例为1 015例,晚发现率为44.15%,各年度的HIV/AIDS病例晚发现比例差异无统计学意义(x2=6.817,P=0.230),多因素logistic回归分析模型显示,诊断时年龄、民族、户籍、样本来源是HIV/AIDS病例晚发现的主要影响因素.年龄越大病例晚发现率越高(x2=85.613,P<0.001),≥60岁年龄组的病例晚发现风险是0~<20岁年龄组的6.459倍(OR=6.459,95%CI:2.577~16.190),回族病例晚发现风险是汉族的1.289倍(OR=1.289,95%CI:1.024~1.623),其他民族病例晚发现风险比汉族低(OR=0.638,95%CI:0.441~0.924),外省户籍病例晚发现风险比本省户籍病例低(OR=0.548,95%CI:0.332~0.934),检测咨询(OR=0.506,95%CI:0.409~0.627)及其他途径发现的病例(OR=0.660,95%CI:0.508~0.857)晚发现风险低于医疗机构.结论 青海省2017-2022年新报告的HIV/AIDS病例晚发现比例高于全国水平,下一步需提升HIV检测覆盖率,针对中老年人、本地常住居民主动开展HIV动员检测,重点加强对少数民族人群的HIV检测宣传,扩大HIV自愿咨询检测(voluntary counseling and testing,VCT)门诊检测覆盖率,提高医疗机构中重点科室主动提供HIV检测咨询服务的积极性.
Late detection of new HIV/AIDS cases in Qinghai Province from 2017-2022 and its influencing factors
Objective To analyze the late detection status of newly reported cases of human immunodeficiency virus/acquired immune deficiency syndrome(HIV/AIDS)in Qinghai Province from 2017 to 2022 and the related influencing factors,so as to provide the basis for formulating the early detec-tion strategy of HIV/AIDS cases in Qinghai Province.Methods The ewly reported HIV/AIDS data was download from the AIDS integrated prevention and control information management system in Qinghai Province from 2017 to 2022.We described the basic demographic characteristics of its late detection cases and analyzed the influencing factors of late detection using single factor analysis and multivariable logistic regression models.Results There were a total of 2 299 newly reported HIV/AIDS cases in Qinghai Province from 2017 to 2022,of which 1 015 were late detected cases,corresponding to a late detection rate of 44.15%.There was no statistically significant difference in the proportion of HIV/AIDS cases detected late across different years(x2=6.817,P=0.230).Multivariable logistic regression analysis showed that age,nationality,registered residence and sample source were the main factors influencing the late detection of HIV/AIDS cases at diagnosis.The older the age,the higher the rate of late detection of cases(x2=85.613,P<0.001).The risk of late detection in the age group ≥ 60 years old was 6.459 times higher than that in the age group 0-<20 years old(OR=6.459,95%CI:2.577-16.190).The risk of late detection of HIV/AIDS cases among Hui ethnicity was 1.289 times higher than that of the Han ethnicity(OR=1.289,95%CI:1.024-1.623),while the risk of late detection for cases from other ethnicities was lower than that of the Han ethnicity(OR=0.638,95%CI:0.441-0.924).The risk of late detection for cases with household registration from other provinces was lower than that of cases with local household registration(OR=0.548,95%CI:0.332-0.934).Cases detected through testing consultation(OR=0.506,95%CI:0.409-0.627)and other methods(OR=0.660,95%CI:0.508-0.857)had a lower risk of late detection compared to those detected in medical institutions.Conclusions The proportion of late detection of newly reported HIV/AIDS cases in Qinghai Province from 2017 to 2022 was higher than the national level.The next step is to increase the coverage of HIV testing,actively carry out HIV mobilization testing for middle-aged and elderly people and local residents,focus on strengthening HIV testing promotion for ethnic minoritiy populations,expand the coverage of voluntary counseling and testing(VCT)outpatient testing,and increase the enthusiasm of key departments in medical institutions to actively provide HIV testing and consulting services.

Human immunodeficiency virusLate discoveryInfluencing factor

匡嘉影、董世存、马斌忠、梁达、李积平

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青海省疾病预防控制中心传染病预防控制所性病艾滋病防治科,西宁 810007

人类免疫缺陷病毒 晚发现 影响因素

2024

中华疾病控制杂志
中华预防医学会 安徽医科大学

中华疾病控制杂志

CSTPCD北大核心
影响因子:1.862
ISSN:1674-3679
年,卷(期):2024.28(12)