目的 了解合肥市男男性行为者(men who have sex with men,MSM)对艾滋病(acquired immune deficiency syndrome,AIDS)暴露前预防(pre-exposure prophylaxis,PrEP)和暴露后阻断(post-exposure prophylaxis,PEP)的认知与服务使用状况.方法 2022年4-5月采用滚雪球抽样方法,依托社会组织在MSM活跃的QQ群、微信群等自媒体网络平台招募符合条件的研究对象,通过问卷星系统收集人口学信息、行为学特征、PrEP和PEP知识知晓与服务使用情况,采用logistic回归分析模型分析影响PrEP和PEP使用的相关因素.结果 共调查800人,83.1％听说过PrEP,其PrEP知识知晓率、咨询过PrEP和使用过PrEP的比例分别为64.5％、42.6％和20.0％;87.1％听说过PEP,其PEP知识知晓率、咨询过PEP和使用过PEP的比例分别为49.6％、46.1％和21.5％.多因素logistic回归分析模型显示,影响MSM使用PrEP的相关因素包括近6个月性行为中使用过新型毒品(OR=1.98,95％CI:1.15～3.42)和咨询过PrEP(OR=7.96,95％CI:4.51～14.05).影响MSM使用PEP的相关因素包括知晓PEP知识(OR=1.97,95％CI:1.20～3.22)和咨询过 PEP(OR=13.44,95％CI:7.10～25.42).结论 合肥市MSM听说过PrEP和PEP的比例较高,但对PrEP和PEP知识的知晓率和使用率均较低,应将PrEP和PEP宣传教育与现有AIDS咨询检测服务相结合,全方位、多渠道提高MSM的PrEP和PEP知识知晓率,促进有高危行为的MSM尽快使用PrEP或PEP.
A cross-sectional study of the awareness and utilization of HIV pre-exposure prophylaxis and post-exposure prophylaxis among MSM
Objective To study the awareness and utilization of HIV pre-exposure prophylaxis(PrEP)and post-exposure prophylaxis(PEP)among the men who have sex with men(MSM)in Hefei City.Methods In April-May 2022,a snowball sampling method was used,relying on social organization to recruit eligible survey objects from self-media online platforms,such as QQ groups and WeChat groups,which are active in MSM.Their demographic information,behavioral characteristics,awareness of PrEP and PEP knowledge,and service use were collected through the questionnaire star system,and logistic regression models were used to analyze the relevant factors influencing the use of PrEP and PEP.Results A total of 800 MSM were surveyed,83.1％had heard of PrEP,and the proportions of those who had heard of PrEP who knew about PrEP,consulted PrEP and used PrEP were 64.5％,42.6％and 20.0％respectively.87.1％had heard of PEP,and the proportions of those who had heard of PEP who knew about PEP,consulted PEP and used PEP were 49.6％,46.1％and 21.5％.Multifactorial logistic regression analyses showed that factors associated with PrEP utilization in the MSM included having used a new drug during sexual activity in the last 6 months(OR=1.98,95％CI:1.15-3.42)and having consulted PrEP(OR=7.96,95％CI:4.51-14.05).Factors associated with PEP utilization in the MSM included awareness of PEP knowledge(OR=1.97,95％CI:1.20-3.22)and having consulted PEP(OR=13.44,95％CI:7.10-25.42).Conclusions The MSM in Hefei City had heard of PrEP and PEP at a relatively high rate,but the rate of awareness and utilization of PrEP and PEP were both low.It should combine PrEP and PEP publicity and education with the existing HIV counselling and testing services to enhance the awareness rate of PrEP and PEP among the MSM in an all-rounded and multi-channel manner,and to promote the use of PrEP or PEP for MSM having high-risk behaviors as soon as possible.
Human immunodeficiency virusMen who have sex with menPre-exposure prophylaxisPost-exposure prophylaxis
万方数据
维普
