Effect of Curcumin on Growth Performance and Antioxidant in Weanling Pigs Counteracting Escherichia coli
To determine the effect of curcumin on growth performance and antioxidant properties in weaning piglets,forty piglets counteracting enterotoxigenic Escherichia coli (1 × 109cell per head) during adaptation period were randomly assigned to four groups with ten replicates per group and 1 piglet in each replicate for a 21 day experiment.The piglets in control group were fed basal diet,and the experimental groups were fed the basal diet supplemented with 50 mg/kg quinocetone,200 mg/kg and 400 mg/kg curcumin,respectively.The results showed as follows.,supplementation with 50 mg/kg quinocetone or 400 mg/kg curcumin significantly reduced the ratio of feed to gain (P<0.05).The concentrations of glutathione peroxidase (GSH-PX),catalase (CAT),superoxide dismutase (SOD) activities and total antioxidant capacity (T-AOC) in serum were significantly increased (P< 0.05);and malondialdehyde (MDA) content was significantly decreased (P<0.05) by addition of 400mg/kg curcumin.These results suggest that the addition of curcumin promotes growth performance,as well as enhances antioxidant ability of piglets.