Progress of Drug Resistance Mechanisms of Pasteurella multocida
Pasteurella multocida is a Gram-negative bacterium that infects a wide range of hosts and can cause avian cholera,swine atrophic rhinitis,swine pneumonia,haemorrhagic septicaemia in cattle,sheep and rabbits.With the widespread use of antibiotics,the resistance of pathogenic bacteria is increas-ing every year.Studies in recent years have even more often found that pathogenic bacteria can develop strong resistance to β-lactams,macrolides,quinolones,tetracyclines,chloramphenicol and sulphonamide antibiotics.This paper summarizes the drug susceptibility and resistance mechanisms of Pasteurella mul-tocida to six types of antibiotics,providing a theoretical basis for the research of new drugs and the estab-lishment of novel therapies.