BMP亚家族成员中影响绵羊繁殖性能的基因研究进展
Progress in Genetic Research on the Effect of BMP Subfamily Members on Sheep Reproductive Performance
刘梦兰 1邵旭文 1单雪松 1姜怀志1
作者信息
- 1. 吉林农业大学动物科学技术学院,长春 130118;农业农村部畜禽资源(羊)评价利用重点实验室,长春 130118
- 折叠
摘要
排卵数和产羔数是反映绵羊繁殖性状的关键性指标,也是绵羊重要的经济性状,二者属于中低遗传力性状,受基因型、环境和营养状况等多重因素共同影响.由BMP、GDF和AMH等组成的BMP亚家族是TGF-β超家族的重要组成部分,BMPR1B、BMP15和GDF9是目前与绵羊繁殖性能相关性研究最为深入的基因.该文对BMP亚家族成员中提升绵羊排卵数及产羔数的基因的SNP位点进行归纳,总结了这些基因影响繁殖性能的SNP位点的发现,品种、定位、表型,以及对排卵数和产羔率的影响机制,旨在为绵羊多胎品种的选育和高效繁殖提供理论参考.
Abstract
Ovulation number and litter size are both the key indicators reflecting the reproductive traits of sheep and important economic traits of sheep.As being low to medium heritability traits,they are af-fected by multiple factors such as genotype,environment and nutritional status.The BMP subfamily,which consists of BMP,GDF and AMH,is an important part of TGF-β superfamily.BMPR1B,BMP15 and GDF9 are currently the most intensively studied genes related to sheep reproductive performance.In this paper,the SNP loci of genes that increase the number of ovulation and litter size of sheep in BMP sub-family members are summarized.The discovery,location,phenotype of SNP loci of these genes affecting reproductive performance,as well as the mechanism of their effects on the number of ovulation and litter size are summed up.The aim is to provide a theoretical reference for the breeding and efficient reproduction of sheep's multiple births.
关键词
突变位点/繁殖性状/BMPs/主效基因/绵羊Key words
genetic mutations/productive traits/bone morphogenetic protein(BMPs)/major genes/sheep引用本文复制引用
基金项目
吉林省科技发展计划项目(20200402039NC)
出版年
2024
国家科技期刊平台
NSTL
万方数据