Mycotoxin,as an anti-nutritional factor,is of hepatotoxicity,mutagenicity,nephrotoxicity,immunosuppression and carcinogenicity.Pollution of mycotoxins contributes to the losses in yield and e-conomy around the world.Diet with high mycotoxin levels can do acute or chronic harm to the health of animals and humans.This paper summarizes the harm and biodegradation strategies of common mycotox-ins,which lays a good foundation for in-depth study of microbial degradation of mycotoxins.