In order to study the correlation between the expression of annexin A2(ANXA2)gene and the amino acid and fatty acid contents in muscles of Songliao black pig,New Jilin black pig and Min pig,the relative expression of ANXA2 gene in the longissimus dorsi muscle was detected by real-time fluores-cence quantitative PCR,and the correlation between the expression of ANXA2 gene with intramuscular fat and the content of amino acids and fatty acids in the muscle was analyzed.The results showed that the expression trend of ANXA2 gene in the three breeds was Songliao black pig>New Jilin black pig>Min pig.There was no significant correlation between the expression level of ANXA2 gene with intramuscular fat and amino acid content in the three pig breeds(P>0.05).ANXA2 gene expression level exhibited sig-nificantly negative correlation with monounsaturated fatty acids in New Jilin Black pigs(P<0.05)and pal-mitic acid in Min pigs(P<0.05).In summary,ANXA2 could affect meat quality by regulating the fatty acids content and be used as one of the candidate genes for evaluating meat quality.